#Euthyroid sick syndrome mayo clinic free

The cut-off value of FT3 for 28-day mortality was 2.88 pmol/L, and the 28-day mortality rate and hospitalization expenses in the ICU were higher in patients with ESS.

#Euthyroid sick syndrome mayo clinic free

A univariable analysis identified ESS, FT3, free thyroxine (FT4)/FT3, the APACHE II score, the sequential organ failure (SOFA) score, the duration of mechanical ventilation, creatinine (CREA) levels, the oxygenation index (HGB), white blood cells, albumin (ALB) levels, age, and brain natriuretic peptide (BNP) levels as factors associated with 28-day mortality (all P < 0.05). Levels of FT3 (P < 0.001) and FT4 (P = 0.001) were lower, while the 28-day mortality rate (P < 0.001) and hospitalization expenses in the ICU (P = 0.001) were higher in the ESS group. Results: Out of a total of 305 patients, 118 (38.7%) were in the ESS group.

The relationship between ESS and prognostic indicators in patients admitted to the ICU was evaluated, and the FT3 cut-off points that could be associated with 28-day mortality were examined. The patients were divided into ESS (FT3 < 3.28 pmol/L) and non-ESS groups. Baseline variables and data on the occurrence of low FT3 were collected.

Methods: This prospective observational study included patients admitted to the ICU of The Third Hospital of Hebei Medical University between February and November 2018. This study evaluated the relationship between ESS and prognostic indicators in patients admitted to an ICU and examined the free T3 (FT3) cut-off points that could be associated with 28-day mortality.

Objective: A low concentration of plasma triiodothyronine (T3) indicates euthyroid sick syndrome (ESS), which could be associated with a poor outcome in patients in intensive care units (ICUs).

3Department of School Infirmary, Infirmary of Shijiazhuang Institute of Technology, Shijiazhuang, China.

2Department of Critical Care Medicine, The Third Hospital of Hebei Medical University, Shijiazhuang, China.

1Department of Endocrinology, The Third Hospital of Hebei Medical University, Shijiazhuang, China.

Jianying Guo 1,2* Yanyan Hong 3 Zhiyong Wang 2 Yukun Li 1*